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环境健康研究中心

  
 

  姓名:马瑞雪 

  职称/职务:副研究员 

  毕业院校:中国农业大学   农产品安全专业  博士 

  个人简况: 

  主要从事新兴有机污染物环境行为、生态毒理与风险评价方面研究。近年来,主持或参加国家重点研发计划子课题、环保部部门预算重大专项、国家和省市各级自然科学基金、中央公益性科研业务等科研项目十余项,已发表SCI论文24篇,累计他引次数超过300,并有两篇分别入选ESI高被引论文和热点论文。 

  目前主持的研究课题和任务如下: 

  目前主持广东省自然科学基金“微塑料与手性PPCPs美托洛尔对草鱼的复合生态效应研究”(2018A030313945,在研)、广州市科技创新计划项目“基于保护人体健康的珠江四溴双酚A水质基准研究”(201804010234, 在研);完成一项中央级公益性科研院所基本科研业务费专项资金重点项目“水环境中塑料微球与TBBPA的生态效应和污染规律”(2017-2018,结题)以及新兴有机污染物控制北京市重点实验室开放基金“北京地表水中手性药物的归趋与对映体选择性环境行为”(2016-2017,结题)。作为项目骨干参与国家自然科学基金重点项目“典型污染源四溴双酚A及其降解转化产物的环境暴露特征与健康风险”(D070804)、国家自然科学基金面上项目“微塑料对四溴双酚A在食用贝类中生物有效性的影响”(21876059)、国家重点研发计划“场地土壤环境风险评估方法和基准”(2018YFC1801102)、水体污染控制与治理科技重大专项 (2017ZX07202) “重污染区(武进)水环境整治技术集成与综合示范项目”、广东省科技计划项目“基于风险地图的垃圾焚烧厂环境与健康风险交流技术研究”(2017A020216017)等科研项目。 

  近期代表论著(或主要论文论著) 

  1. Ma Ruixue, Qu Han, Wang Bin, et al. Simultaneous enantiomeric analysis of non-steroidal anti-inflammatory drugs in environment by chiral LC-MS/MS: A pilot study in Beijing, China. Ecotoxicology and environmental safety, 2019, 174: 83-91.   

  2. Qu Han, Ma Ruixue (co-first author), Wang Bin, et al. Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs. Journal of hazardous materials, 2019, 370: 203-211.   

  3. Qu Han, Ma Ruixue (co-first author), Wang Bin, et al. Effects of microplastics on the uptake, distribution and biotransformation of chiral antidepressant venlafaxine in aquatic ecosystem. Journal of hazardous materials, 2018, 359: 104-112.   

  4. Yu Yunjiang, Ma Ruixue* (corresponding author), Yu Lehuan, et al. Combined effects of cadmium and tetrabromobisphenol a (TBBPA) on development, antioxidant enzymes activity and thyroid hormones in female rats. Chemico-Biological Interactions, 2018, 289: 23-31.  

  5. Ma Ruixue, Wang Bin, Yin Lina, et al. Characterization of pharmaceutically active compounds in Beijing, China: Occurrence pattern, spatiotemporal distribution and its environmental implication. Journal of hazardous materials, 2017.2.5 323:147-155.   

  6. Ma Ruixue, Wang Bin, Lu Shaoyong, et al. Characterization of pharmaceutically active compounds in Dongting Lake, China: Occurrence, chiral profiling and environmental risk. Science of the Total Environment, 2016.7.10 557-558: 268-275. (ESI Highly cited paper)  

  7. Ma Ruixue, Qu Han, Liu Xia, et al. Enantioselective metabolism of the chiral herbicide diclofop-methyl and diclofop by HPLC in loach (Misgurnus anguillicaudatus) liver microsomes in vitro. Journal of Chromatography B, 2014, 969: 132-138.  

  8. Ma Ruixue, Liu Donghui, Qu Han, et al. Enantioselective toxicokinetics study of the bioaccumulation and elimination of α-hexachlorocyclohexane in loaches (Misgurnus anguillicaudatus) and its environmental implications. Chemosphere, 2013, 90(7): 2181-2186.   

  9. Qu Han, Ma Ruixue, Wang Fang, et al. The effect of biochar on the mitigation of the chiral insecticide fipronil and its metabolites burden on loach (Misgurnus. anguillicaudatus). Journal of hazardous materials, 2018, 360: 214-222.   

  10. Yin Lina, Ma Ruixue, Wang Bin, et al. The degradation and persistence of five pharmaceuticals in an artificial climate incubator during a one year period. RSC Advances, 2017, 7(14): 8280-8287.  

  11. Qu Han, Ma Ruixue, Liu Donghui, et al. Environmental behavior of the chiral insecticide fipronil: Enantioselective toxicity, distribution and transformation in aquatic ecosystem. Water research, 2016, 105: 138-146.  

  12. Qu Han, Ma Ruixue, Liu Donghui, et al. The toxicity, bioaccumulation, elimination, conversion of the enantiomers of fipronil in Anodonta woodiana. Journal of hazardous materials, 2016, 312: 169-174.  

  13. Qu Han, Ma Ruixue, Liu Donghui, et al. Enantioselective toxicity and degradation of the chiral insecticide fipronil in Scenedesmus obliguus suspension system. Environmental toxicology and chemistry, 2014, 33(11): 2516-2521.   

  14. Qu Han, Wang Peng, Ma Ruixue, et al. Enantioselective toxicity, bioaccumulation and degradation of the chiral insecticide fipronil in earthworms (Eisenia feotida). Science of the Total Environment, 2014, 485: 415-420.  

  15. Zhou Gaoxin, Liu Donghui, Ma Ruixue, et al. Enantioselective kinetics of α-hexachlorocyclohexane in earthworm (Eisenia fedtia) and forest soil. Chirality, 2012, 24(8): 615-620.   

  16. Chen Haibo, Wang Chen, Li Hui, Ma Ruixue, et al. A review of toxicity induced by persistent organic pollutants (POPs) and endocrine-disrupting chemicals (EDCs) in the nematode Caenorhabditis elegans. Journal of environmental management, 2019, 237: 519-525.   

  17. Zhang Zhixia, Wang Bin, Yuan Honglin, Ma Ruixue, et al. Discharge inventory of pharmaceuticals and personal care products in Beijing, China. Emerging Contaminants, 2016, 2(3): 148-156.  

  18. Yu Yunjiang, Yu Ziling, Chen Haibo, Han Yajing, Xiang Mingdeng, Chen Xichao, Ma Ruixue, Wang Zhengdong. Tetrabromobisphenol A: Disposition, kinetics and toxicity in animals and humans. Environmental Pollution, 2019, 253, 909-917.   

  19. Yu Yunjiang, Yu Ziling, Xiang Mingdeng, Zhou Zhixiang, Hu Guocheng, Zhang Yanping, Ma Ruixue, Li Hui. Screening and prioritization of chemical hazards for deriving human health ambient water quality criteria in China. Journal of environmental management, 2019, 245, 223-229.   

  20. Yu Yunjiang, Yu Ziling, Sun Peng, Lin Bigui, Li Liangzhong, Wang Zhengdong, Ma Ruixue, Xiang Mingdeng, Li Hui, Guo Shu. Effects of ambient air pollution from municipal solid waste landfill on children's non-specific immunity and respiratory health. Environmental pollution, 2018, 236, 382-390.   

  21. Yu Yunjiang, Xiaohui Zhu, Junyan Zhu, Li Liangzhong, Zhang Xiaohua, Xiang Mingdeng, Ma Ruixue, Yu Lehuan, Yu Ziling, Wang Zhengdong. Rapid and simultaneous analysis of tetrabromobisphenol A and hexabromocyclododecane in water by direct immersion solid phase microextraction: Uniform design to explore factors. Ecotoxicology and environmental safety, 2019, 176: 364-369. 

  22. Yu Yunjiang, Yu Ziling, Wang Zhengdong, Lin Bigui, Li Liangzhong, Chen Xichao, Zhu Xiaohui, Xiang Mingdeng, Ma Ruixue. Polycyclic aromatic hydrocarbons (PAHs) in multi-phases from the drinking water source area of the Pearl River Delta (PRD) in South China: Distribution, source apportionment, and risk assessment. Environmental Science and Pollution Research, 2018, 25(13), 12557-12569.  

  23. Yu Yunjiang, Li Liangzhong, Li Hongyan, Yu Xiaowei, Zhang Yanping, Wang Qiong, Zhou Zhixiang, Gao Dandan, Ye Hao, Lin Bigui, Ma Ruixue. In vivo assessment of dermal adhesion, penetration, and bioavailability of tetrabromobisphenol A. Environmental Pollution, 2017, 228, 305-310.   

  24. Yu Yunjiang, Wang Zhengdong, Wang Qiong, Xiang Mingdeng, Zhang Yanping, Ge Qingzhi, Li Liangzhong, Li Hui, Ma Ruixue. Excretion characteristics of tetrabromobisphenol-A in Wistar rats following mouth and nose inhalation exposure. Chemosphere, 2017, 175, 147-152.  

  25. 左优,马瑞雪*(通讯作者),于紫玲,林必桂,于云江,刘珊.反相高效液相色谱法拆分三种非甾体抗炎药物对映体.分析试验室,2019,38(04):465-469. 

  26. 于紫玲,左优,马瑞雪,朱晓辉,朱俊彦,陈希超,刘立婷,向明灯,于云江.QuEChERS/超高效液相色谱-串联质谱法同时测定水产品中四溴双酚A与六溴环十二烷.分析测试学报,2019,38(03):301-306. 

  27. 于紫玲,向明灯,马瑞雪,刘立婷,左优,林必桂,于云江.生物基质中四溴双酚A和六溴环十二烷分析方法研究进展.环境化学,2019,38(03):503-512. 

  28. 尹立娜,王斌,马瑞雪,袁宏林,余刚.手性PPCPs环境行为与效应的对映体选择性.化学进展,2016,28(05):744-753. 

  

  社会任职情况 

  无。 

  荣誉及获奖情况 

  联系方式:Email:maruixue@scies.org;  

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